Exploring New Reactions and Syntheses of Trivalent Iodine Compounds

Trivalent iodine compounds have found widespread applications as oxidants and electrophilic group-transfer agents for organic synthesis. Over the last several years, our group has developed new reactions synthetic methods of a class stable trivalent known benziodoxol(on)es. This article summarizes studies on (1) palladium-catalyzed transformations ethynylbenziodoxol(on)es beyond alkynyl transfer (2) use benziodoxole triflate cationic iodine(III) electrophile functionalization alkynes arenes, illustrating how unique reaction chemistry can be utilized to achieve synthetically attractive open up access previously inaccessible molecular building blocks.